Models built and validated by PK/PD scientists. Guided inputs and interpretation make them accessible to anyone on the team. In the browser, nothing to install, no code.
No signup needed to explore the demo. Early access accounts are free.
Biologics PK/PD models written and calibrated by pharmaceutical scientists, not generated by AI. Includes specialized ADC disposition modeling that reflects real discovery-stage assumptions, uncertainties, and biological constraints.
Every input comes with sensible defaults, plausible ranges, and clinical priors from approved biologics, so you can set up a credible simulation without being a modeling expert.
Every parameter, assumption, and output remains visible, editable, and scientifically interpretable.
From model selection to AI-assisted interpretation in minutes
Select from biologics PK/PD, ADC disposition, T-cell engager (TCE) pharmacology, TMDD, linear PK, NCA, or DDI models built by biologics PK scientists
Configure dosing and PK parameters guided by clinical priors from approved biologic therapeutics
Run instant simulations with real-time visualization and live parameter adjustments
Ask Pylot AI what the results mean, how they compare to approved drugs, and what to check next, grounded in the simulation on screen
Simulation, interaction analysis, species translation, and built-in expert guidance
Interactive simulations with live parameter adjustments and instant visualization of concentration-time profiles.
Simulate total antibody, conjugated ADC, and free payload simultaneously, and see how dosing and deconjugation shift every analyte at once.
CYP-mediated and transporter-mediated DDI assessment, classified into weak, moderate, and strong bands by predicted AUC ratio, including ADC payload-specific profiling.
Translate cynomolgus or rat ADC data into human predictions using precedent-based, allometric, or hybrid scaling, with the rationale shown parameter by parameter.
CD3 bispecific / T-cell engager pharmacology with blood and tumor trimer formation and IL-6-driven cytokine release syndrome (CRS) prediction.
Built-in ADC and TCE consultants provide decision support on model choice, study design, translational PK, and risk questions.
Written and calibrated by pharmaceutical scientists, not generated by AI. Biologics-focused, with deep ADC specialization.
Population PK and pediatric/geriatric scaling are on the roadmap.
Calibrated against published clinical data from approved ADC and biologic therapeutics.
Run an expert-built model in the browser and see every parameter behind it
Early access accounts are free.